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Informative Articles

Beating Depression
Depression hits many of us at different times during our lives. The symptoms are commonly known: being tired all the time, low self-esteem, no self-confidence, disturbed sleep, concentration impaired and no interest in life. Depression is not just...

Beating Depression By Action
Depression can come on us at any time of the year. Sometimes, holidays are the worst times for those that feel this down-in-the-dumps fear and worry and things just seem to happen to make us feel gloomy and sad. Note that this feeling happens to all...

Depression And Celiac Disease
It is quite common for people who have been diagnosed as having Coeliac Disease to find themselves feeling depressed and anxious. For many there is a link between food and a sense of control over their lives. Celiacs are faced with something over...

Get Rid Of Depression Once And For All
Depression is something that will occur in many people's lives, for various reasons. But the "normal" occurrence of a plunge in mood due to stressful events in your life, usually doesn't last very long, before a person's natural resilience responds...

How to Step Out of the State of Depression
Depression is one of the most common mental illnesses. At least eight percent of adults in the US experience serious depression at some point during their lives. The illness affects all people, regardless of sex, race, ethnicity or socioeconomic...

Mood Disorders And Depression
Mood Disorders And Depression By Jeannie Crabtree We all suffer with bad moods from time to time. But if you are someone who is in a bad mood or depressed much of the time, take heart. There are natural remedies to help with balancing your...

Stress and Depression are Killing Us!
A short generation ago, families could set their watch by the time the father got home from work each day. My dad always walked through the front door at precisely 6 PM and supper was served at 6:10. We'd all sit around the table...

The End of Extreme Depression, Self-injury, Incited violence & Suicide
Please help end suicide (and extreme depression, self-injury & incited violence) and spread the web addresses everywhere, including the internet: SUICIDE VACCINE, a "figure of speech", is a solution to ending suicide, a life preserver made up of...

WHAT YOU NEED TO KNOW ABOUT DEPRESSION
What does depression mean to you? Depression is a very serious mood disorder that can affect anyone regardless of age, gender, race, social status or ethnicity. Depression is an illness that affects your body, mind, disposition, sleep and...

When Someone You Know Has To Deal With Depression, Anxiety And Fear
What do you do when you someone you know has to deal with persistent fears and anxieties or even depression? Well the first thing you need to do is to get the person to seek the services of a professional and/or counselor who can lead them in the...

 
 
 
Depression Series (Part 3): What to Do with Those Antidepressant Side Effects?

Maria’s depression was difficult to treat. As you can recall, various medications had been tried to no avail. But after several months of treatment, Maria has eventually become stable on a combination of two antidepressants.

She’s now able to do her usual activities and is motivated to go back to work — something she has struggled to do for a while. Despite her improvement, antidepressant side effects have emerged and are bothersome. Maria begins to consider discontinuing her medications prematurely.

Antidepressant side effects are real and negatively affect patient’s compliance. Many patients like Maria consider stopping the medication even at the risk of relapse because of distressing side effects.

How do you deal with some of the common antidepressant side effects?

Insomnia

Some antidepressants e.g. SSRIs (serotonin-reuptake inhibitor) are highly stimulating that they cause insomnia when taken in the afternoon or at bedtime. Take this type of medication in the morning. Discuss with your physician the use of a sedating medication such as trazodone or sedative-hypnotic drug along with the antidepressant. If you want to take only one pill, talk to your doctor about switching to a sedating antidepressant such as mirtazapine.

Moreover, sleep hygiene should be practiced. Avoid naps and intake of caffeinated drinks such as coffee and soda in the afternoon and evening. Involve in regular exercise and physical activities during the day. Moreover, use the bedroom only for sleep and sex and not for recreational activities.

Weight gain

Regular exercise is weight gain’s antidote. If no medical contraindication, you may consider jogging, walking, or swimming. To reduce some excess and unwanted fat, keep yourself busy with physical and recreational activities.

How about diet? Diet has always been a part of any weight control regimen. Monitor your carbohydrate intake. Ice cream, chocolates, and other high-caloric foods should be reduced. If none of the above works, talk to your doctor about switching pills.

Sexual dysfunction

Sexual dysfunction happens too often but is rarely asked or discussed in the clinic. Some physicians and patients feel embarrassed about this subject. When you have concerns, be open to your physician. Discuss the possibility of switching medication to an antidepressant (such as bupropion or mirtazapine) that doesn’t significantly impair sexual functioning. Also, talk to your doctor about adding another drug such as bupropion, yohimbine, or even mirtazapine to counteract the sexual side effect.

How do you know if the sexual dysfunction is from the pill rather than from depression? If the dysfunction persists despite successful remission of depression, then you should consider other causes such as drug-induced dysfunction or other medical causes e.g. diabetes.

Dry mouth

 




Tricyclic antidepressants (TCA e.g. amitriptyline) are notorious for causing dry mouth. Why? These drugs have distressing anticholinergic side effects. Avoid this type of drugs. If TCA is still considered, talk about the use of desipramine or nortriptyline. Compared to other TCAs, these two drugs have less anticholinergic effects.

Moreover, try ice chips. Frequent sips of water should also help. To avoid dental cavities, try sugarless candy or sugar-free gum.

Constipation

Like dry mouth, constipation is usually caused by TCAs. To prevent it from happening, drink enough water and eat high fiber foods such as vegetables and fruits. Consider stool softeners if the above interventions fail. If possible, avoid TCAs.

Nausea and vomiting

Patience is the key in dealing with these side effects. Frequently, patients develop tolerance within two weeks. Take the medication with food. If ineffective, talk to your doctor about possibly reducing the dose of your medication or trying antacid or bismuth salicylate (Pepto-Bismol)

Memory lapses

If given permission by your doctor, try to reduce the dose. Also, discuss with your physician about switching antidepressant (especially if dose reduction doesn’t alleviate your concern) and avoiding drugs with anticholinergic side effects.

Moreover, don’t mix the antidepressant with alcohol. The alcohol-drug interaction can only worsen the memory and cognitive functioning. While on psychotropic drugs, be careful driving and using mechanized equipment.

Dizziness

While still in bed, sit up for 30 seconds, then stand up for another 30 seconds while holding a rail, a table, or a chair before walking. Take the medication at bedtime. Some people use support hose with success.

Agitation or anxiety

Some people benefit from a brief use of benzodiazepine such as lorazepam. Breathing exercises and progressive muscle relaxation should also help.

In general, some side effects such as gastrointestinal upset and insomnia may resolve in a few days. Patience is the key. However, be on guard. When they occur, address them promptly. I’m not however suggesting that you should be your own doctor.

Collaborating with your doctor is an effective way to cope with mental illness and medication problems. Treatment options such as the need to switch or reduce medications should be discussed in an open and accepting manner.


About the Author

Copyright © 2003. All rights reserved. Dr. Michael G. Rayel – author (First Aid to Mental Illness–Finalist, Reader’s Preference Choice Award 2002), speaker, workshop leader, and psychiatrist. Through the CARE approach, Dr. Rayel helps individuals recognize the early signs of mental illness and provide early intervention. To receive free newsletter, visit www.drrayel.com. His books are available at major online bookstores